Saturday, December 20, 2008
This looks like some kind of FOOD
Yesterday my friens in Year 3 "they were studying metabolic, endocrine and reproductive systems" did thier OSPE exam, OSPE stands for Objective structure practical examination, it's basically the lab exam, after thier exam I asked them what did they find peculiar, they said that there was a question about bacteria which its genus name is Mycoplasma , I said oh that's the one that looks like "fried egg" on agar culture and they said yes this is the one, the question was likely and more conveniently about Mycoplasma Genitalium or it could be about the more common Mycoplasma Pneumoniae as Microbiology people don't know what the exam is about they prepare slides and put questions about whatever in thier minds.Coincidentally yesterday I watched the Annual Richard Demblebey lecture and it was done by Dr. Craig Venter and entitled "A DNA driven world", Dr. Venter is working on genome projects and his own genome was the one that was revealed last year, also he is working in his institute with a team of scientists headed by Nobel laurete Dr. Hamilton Smith, they are working on synthesizing a NEW LIFE, they did it first with a virus that they demonstrated a fast method of synthesizing its genome back in 2003, and now they are working on Mycoplasma Genitalium, whose genome is the smallest of any known natural organism that can be grown in free culture "of course viruses can not be cultured". Now they are trying to "play games" with this bacteria's genome and a version of the minimal 381-gene chromosome has been synthesized, it is intended to be transplanted into the nucleoid of a M. genitalium cell to create Mycoplasma laboratorium"lovely name". The team had demonstrated the process of transplanting a (non-synthetic) genome from one Mycoplasma species to another in June 2007.Other question that my year 3 friend were asked yesterday was about small-cell carcinoma of the lung and they asked them what do you expect the adrenal gland of the patient to be, they put three pictures one normal and one atrophied and another hypertrophied, and also they asked about a syndrome that the patient could have, I told them this is a good question, of course they figured out the hypertrophy but did not get the two syndromes which I answered without thinking so I got the feeling of "good, this is something I remember", Now cancer cells usually do stupid things that make them cancerous, they sometimes like in this case secrete things that they have nothing to do with, in small cell carcinoma of the lung "AKA oat cell carcinoma" they name it as food-like appearence,which they do not use anymore, the cancer could produce ACTH and ADH hormones, so the adrenal gland will become under the effect of that ectopic ACTH wthout any chance of negative-feedback mechanism, this is a cushing's syndrome secondary to that ectopic secretion of ACTH,and the production of ADH will cause a syndrome known as syndrome of inapropriate antidiuretic hormone. in which the person will have more retention of free water and hyponatremia secondary to his excess amount of water in his plasma and thus hypotonia, and of course the management would be simply restricting water-intake"review unit one problem one, clinical biochemistry book,chapter of hyponatremia :)".
Wednesday, September 10, 2008
Ephemera! Ephemera!
Roy Cohn was very infamous about his role during the trial of Julius and Ethel Rosenberg, in the 50s of the previous century, in the third chapter of Angels in America Joe who was also ill for the previous days comes to Roy and tells him that he is refusing the offer so they had a conversation and a fight if it can be called so.
Roy is hopeless, diagnosed with AIDS in the 80s which means death, he wants his clerk lawyer Joe to take the job so that he can help him by being his man in the justice department in Washington, what he called in the first chapter "clout", well, Ahmad has nothing else to say so let's read another piece of Kushner's masterpiece
Joe:I can't go to Washington. The answer's no. I'm sorry.
Roy:Oh, well. Apologies. I don't see that there's anyone asking for apologies.
-I'm sorry, Roy.
-Oh, well, apologies.
-My wife is missing. My mother's coming from Salt Lake to help look, I guess. I'm supposed to be at the airport picking her up now, but.... I just spent two days in a hospital, Roy, with a bleeding ulcer. I was spitting up blood. Blood
-Roy:Look, I'm very busy here--
-Joe:It's just a job.-
-A job? A job? Washington? Dumb Utah Mormon hick .
-Joe:Roy..
-Washington? When Washington called me, I was younger than you. You think I said, "Oh, , no, I can't go. "l got little moral nosebleed to boot"? When Washington calls you, my pretty young punk friend, you go.. or you'll damn yourself... 'cause the train has pulled out of the station and you're out! Nowhere. Out in the cold. Damn you, Mary Jane. Get out of here!
-Joe:Look, just let me--
-Roy:What, explain? Ephemera! Explain. You broke my heart, explain that.
-I love you, Roy. There's so much that I want to be. What you see in me.... I wanna be a participant in the world. In your world, Roy. I wanna be capable of that. I've tried, really, I have. But I can't do this. Not because I don't believe in you, but because I believe in you so much. And what you stand for at heart. The order, the decency. I would give anything to protect you, but there are laws I can't break. It's too ingrained, it's not me. There's enough damage I've already done. Maybe you're right. Maybe I'm dead.
Roy:You're not dead, boy, you're a sissy. You love me, that's moving. I'm moved. It's nice to be loved. I warned you about her, didn't l, Joe? You don't listen to me. Why? Because you say: "Roy. He's smart, he's a friend... "but, Roy, well, you know, he isn't nice." And you wanna be nice, right? A nice, nice man. You know what my greatest accomplishment was, Joe? In my life, what I am able to look back on and be most proud of? And I have helped make presidents and unmake them. And mayors, and more goddamn judges than anyone in New York City ever... and several million dollars tax-free. And you know what means the most to me? You ever hear of Ethel Rosenberg, Joe?
-Yeah, I guess, yes.
-Yeah, you've heard of Ethel Rosenberg. Maybe even read about her in the history books. If it wasn't for me, Joe, Ethel Rosenberg would be alive today... writing some personal advice column for Ms. Magazine. She isn't. Because during the trial, Joe... I was on the phone every day talking with the judge. Every day, doing what I do best. Talking on the telephone. Making sure that that timid yid nebbish on the bench... did his duty to America, to history. That sweet, unprepossessing woman... two kids, boo-hoo-hoo... reminded us all of our little Jewish mamas, she came this close to getting life. I pleaded till I wept to put her in the chair. Me, I did that. I'd have pulled the switch myself if they let me. Why? Because I hate traitors. Because I hate Communists. Was it legal? Damn legal! Am I a nice man? Damn nice! They say terrible things about me in The Nation. Damn The Nation! You wanna be nice? Or you wanna be effective? You wanna make the law or subject to it? Choose! Your wife chose. A week from today, she'll be back. She knows how to get what she wants. Maybe I'll send her to Washington.
-I don't believe you.
-Gospel.
-Joe:You can't possibly mean what you're saying. You were Assistant United States Attorney on the Rosenberg case. Ex parte communication with the judge during the trial... would be censurable, at least, probably conspiracy. In a case that resulted in execution, it's....
-Roy:What? Murder?
-You're not well, is all.
-What do you mean, I'm not well? Who's not well?
-You said--
-I did? I said what?
-You have cancer.
-No, I don't.
-You told me you were dying.
-What the hell are you talking about, Joe? I never said that. I'm in perfect health. There's not a goddamn thing wrong with me. Shake. It's okay that you hurt me... because I love you, baby Joe. That's why I'm so rough on you. Prodigal son"shouting". The world is gonna wipe its dirty hands all over you.
-lt already has, Roy.
-"fighting Joe"Get out. I'll always be here waiting for you. And what did you want from me? What was all this? What do you want? Treacherous, ungrateful-"Joe strikes back"- Roy:Transgress a little, Joseph. So many laws. Find one you can break.
You must must must!
This is a piece of Dialouge from the play Angels in America by Tony Kushner "also an HBO mini-series by th same name".
Roy Cohn, a McCarthyist attorney" He's a real character" is now diagnosed with AIDS, and is offering a job in Washington to his clerk lawyer Joe who is hesitant about it because of his wife's condition.
here Roy is talking with Joe trying to convince him,
Roy:How long.... How long we known each other? Since 1980. -Right. That's a long time. I feel close to you, Joe. Do I advise you well?
-You've been an incredible friend, Roy.
-I wanna be family. Famiglia... as my ltalian friends call it. La famiglia. Lovely word. It's important for me... to help you, like I was helped.
-I owe practically everything to you, Roy.
-I'm dying, Joe. Cancer.
-Oh, my God.
-Please, let me finish. Few people know this. I'm telling you this because.... I'm not afraid of death. What can death bring that I haven't faced? I've lived. Life is the worst. Listen to me, I'm a philosopher. Joe, you must do this. You must, must. Love, that's a trap. Responsibility, that's a trap, too. Like a father to a son, I tell you this. Life is full of horror. Nobody escapes. Nobody. Save yourself. Whatever pulls on you... whatever needs from you, threatens you. Learn at least this:. What you are capable of... Iet nothing stand in your way.
First Lines
بسم الله الرحمن الرحيم
Here I am, sitting and writing my very first words in this blog and hoping that anyone who gives his/her priceless time to this little page will not be bored, I really hope that I can write something intersting even if it was so for an only person.
In 1657 Blaise Pascal wrote in his 16th letter of "Lettres provinciales" : I have made this [letter] longer, because I have not had the time to make it shorter.
and here I write that I have made this letter short because I have not had the time to make it long.
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